As I've noted before, if your server doesn't require authentication or a port other than 25, you don't need to add it here. The server name in your messages 'Host' header is all that's required.
Name
The Name field will normally be a discriptive name for the server. It can be the same as the SMTP Server field. There is one circumstance when they'll differ. If you have more than one account with a service that requires authentication, you'll need to make each Name unique. It could be as simple as adding a digit to the end of the original value, like this: smtp.myisp.com2.
SMTP Server
This field requires the server name that the email service has given you for SMTP access. Some examples include, mail.myisp.net and smtp.myisp.net. What is most important is that you get it exactly right. Leave off the mail or smtp or whatever the service uses, and you won't have the right server. This is a major pitfall for new users. They swear up and down, stamp their feet and shout that they are positive they have the correct server. Yet they are wrong and cannot see the flaw.
If you get immediately dropped connections when sending, or connections hanging, or other odd error or condition, there's something wrong with your server! It it's the same service as your usual email program, use the exact same server that is in that program.
Port
The standard port for email is 25. The service provides this info. Occasionally you'll encounter a services using an odd port such as 2525. These days services will likely require 587 or 465. Those ports provide for TLS/SSL encrypted connections.
TLS/SSL
If the service requires a port number 587 or 465 the connection will require TLS/SSL encryption. Put in one of those ports and QS will select the correct encryption (TLS for 578, SSL for 465). If the service provides some other odd port number and won't connect, give this a try.
Authentication
Your service will tell you if authentication is required. Your ISP generally won't require it. Other email services will. Encrypted connections always do.
User ID
This is usually your account login ID. One thing to be aware of, some services require only the login name. Others may require the entire email address. Your ISP will generally fall into the earlier group while services such as Yahoo fall into the latter.
Password
This is your account password. Take great care in entering this data.